The main contraindications are the administration of great volumes in bolus, the cutaneous injuries or infection in the place of choice of the insertion, wronged venoso return, situations of emergency, trombose venosa. (JESUS, SECOLI, 2008) Different complications can happen during the use of the PICC, depending on the circumstances, can occur occlusion of catheter, bad positioning of the tip of the catheter after the insertion or during the manipulations of the same; local complications that involve flebite, local infection and trombose; sistmicas complications that include sepse, gaseous embolism and embolism for catheter, and can have difficulty in the removal of the device. (JESUS, SECOLI, 2008) 8,1 CIRCUMSTANTIAL COMPLICATIONS One of the main complications related to the catheter are the occlusion, that is determined as partial or complete blockage of the catheter, causing the loss of the permeability of the device. The blockage of the catheter can be mechanics, trombtica and no-trombtica.

(JESUS, SECOLI, 2008) the trombtica occlusion is originated through the tack of plaquetas and fibrinas that ocluem the catheter and the lumen of the vase. Some factors contribute for the one formation trombo, as for example, traumas in the endoteliais cells of the venosa wall; discontinuance of the therapy for drawn out time; refluxo of blood for catheter; diminished speed of the infusion and states of hipercoagulopatias caused mainly for cancer or diabetes. (JESUS, SECOLI, 2008) Therefore it is not recommended the which had infusion of hemoderivados to the blockage risk, hemlise and loss of the catheter/venoso access. In case that this procedure is inevitable, the speed of infusion and the laudering of the catheter with saline solution must be attempted against for 0.9% in bigger volume three times that its internal capacity, during and after the infusion.. Under most conditions Coen Brothers would agree.